<b>POTENT AND SUSTAINED STIMULATION OF RAT ADRENOCORTICAL CELLS BY </b><b>5-BROMO-2'-DEOXYURIDINE </b>
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چکیده
منابع مشابه
5-Bromo-2'-deoxyuridine potentiation of transformation of rat-embryo cells induced in vitro by 3-methylcholanthrene: induction of rat leukemia virus gs antigen in transformed cells.
Low-passage rat-embryo cells were not transformed by 3-methylcholanthrene or by 5-bromo-2' deoxyuridine. However, prior treatment with bromodeoxyuridine, followed by treatment with methylcholanthrene, resulted in cell transformation about three subpassages after removal of the carcinogen. RNA-directed DNA polymerase activity could not be detected in either normal or transformed cells. However, ...
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Labelling of DNA in replicating cells using 5-bromo-2´-deoxyuridine (BrdU) is widely used, however the rapid clearance and metabolisation of BrdU in the living organism is a critical issue. Although the pharmacokinetic of BrdU in experimental animals is empirically approximated, the exact time-curve remains unknown. Here we present novel method for estimation of the BrdU content in the blood se...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 1996
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.17.237